Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein 10804-HNAC from Sino Biological, Inc.

Product Specs
ItemHuman / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein
CompanySino Biological, Inc.
Price Supplier Page View Company Product Page
Catalog Number10804-HNAC
Conjugate/TagUnconjugated
Purity> 95 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human / rhesus / cynomolgus / canine TGFβ1 consists of 112 amino acids and has a calculated molecular mass of 12.8 kDa. it migrates as an approximately 13 & 26 kDa band in reduced and non-reduced SDS-PAGE respectively, corresponding to the monomer and homodimer
SpeciesHuman, Rhesus, Cynomolgus, Canine
Molecule NameTGFB1
Source/Expression SystemCHO Stable Cells
NCBI Full Gene Nametransforming growth factor beta 1
NCBI Gene AliasesCED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta
Activity1.Measured by its ability to inhibit cell proliferation of Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 0.01-0.1 ng/mL. 2.Human liver cancer organoids were cultured with FGF2(Cat#10014-HNAE), HGF(Cat#10463-HNAS), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), TGFB1(Cat#10804-HNAC), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology
FormatLyophilized from sterile 100mM GLY, 10mM NaCl, pH 3.0

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Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

(1) Development of dual-mode ELISA based on ALP-catalyzed APP hydrolysis for IL-6 detectionJournal of pharmaceutical and biomedical analysisNovember 30, 2023Cao S, Li L, An H, Mao G, Dai J, Ma Y.

(2) Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axisScientific reportsOctober 23, 2023Xia W, Chen X, Zhu Z, Chen H, Li B, Wang K, Huang L, Liu Z, Chen Z.was carried out for further experiment. TGF-β1 was purchased from Sino Biological (Beijing, China, No.10804-HNAC) and dissolved in dimethyl sulfoxide. Cell transfection The lentiviruses carrying Len-sh-MALAT1 and

(3) FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cellsJournal of translational internal medicineSeptember 1, 2023Liu N, Li D, Liu D, Liu Y, Lei J.treatments HK-2 cells were treated with 0, 10, 20, and 40 ng/mL TGF-β1 (Sino Biological, Beijing, China; #10804-HNAC) for 24 h to evaluate the induction of fibrosis by different concentrations of TGF-β1. For silencing

(4) Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated AutophagyCellsJuly 4, 2023Li D, Liu Y, Zhan Q, Zeng Y, Peng Z, He Q, Tan Q, Cao W, Wang S, Wang J.(A8330) was obtained from Solarbio Life Science (Beijing, China). Recombinant human TGF-β1 protein (10804-HNAC) was purchased from SinoBiological (Beijing, China). Rapamycin (HY-10219) was obtained from MedChemExpress

(5) Tissue factor overexpression in triple-negative breast cancer promotes immune evasion by impeding T-cell infiltration and effector functionCancer lettersJuly 1, 2023Ren Z, Xue Y, Liu L, Zhang X, Pei J, Zhang Y, Wang Y, Yu K.

(6) RBBP4 is an epigenetic barrier for the induced transition of pluripotent stem cells into totipotent 2C-like cellsNucleic Acids ResearchJune 23, 2023Wangfang Ping, Yingliang Sheng, Gongcheng Hu, Hongxin Zhong, Yaoyi Li, YanJiang Liu, Wei Luo, Chenghong Yan, Yulin Wen, Xinxiu Wang, et al.penicillin–streptomycin, 0.1 mM 2-mercaptoethanol, 2 ng/ml transforming growth factor-β1 (TGFβ1; Sino Biological, 10804-HNAC), 25 ng/ml fibroblast growth factor 4 (FGF4; Stem Cell, 78103) and 1 μg/ml heparin (Stem Cell, 07980).

(7) Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In VitroInflammationJune 1, 2023Feng Y, Hu J, Liu F, Shang Y.

(8) Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasisSignal Transduction and Targeted TherapyMarch 6, 2023Ying Dong, Hao Hu, Xuan Zhang, Yunkai Zhang, Xin Sun, Hanlin Wang, Weijuan Kan, Min-jia Tan, Hong Shi, Yi Zang, et al.(HY-17471A) were purchased from MedChemExpress. A-769662 (CSN12424) was bought from CNSpharm. TGF-β (10804-HNAC) were purchased from SinoBiological. FGF-2 (MB2458-1) was bought from meilunbio. The siRNA was synthesised

(9) Downregulation of KLF10 contributes to the regeneration of survived renal tubular cells in cisplatin-induced acute kidney injury via ZBTB7A-KLF10-PTEN axisCell death discoveryMarch 6, 2023Zhang Y, Bao S, Wang D, Lu W, Xu S, Zhou W, Wang X, Xu X, Ding X, Zhao S.usage. Cells were collected at different time points after cisplatin treatment. Recombinant TGFβ1 (10804-HNAC, SinoBiological) was dissolved to 2 μg/mL in in sterile 4 mM HCl containing 1 mg/mL bovine serum albumin

(10) Luteolin inhibits the TGF-β signaling pathway to overcome bortezomib resistance in multiple myelomaCancer lettersFebruary 1, 2023Li Z, Wang H, Wang Y, Ma Z, Hu L, Luo S, Gong Y, Zhu L, Gong H, Xiang R, et al.

(11) MiR-552-3p Regulates Multiple Fibrotic and Inflammatory genes Concurrently in Hepatic Stellate Cells Improving NASH-associated PhenotypesInternational journal of biological sciencesJanuary 1, 2023Ma N, Hou A, Pan X, Sun F, Xu X, Yu C, Lai R, Huang R, Gong L, Xie Q, et al.CSN11701) and dissolved in DMSO. The LPS (Sigma-Aldrich, USA, L2630), TGF-β1 (SinoBiological, China, 10804-HNAC) and CCL2 (GenScript, China, Z03292) were dissolved in H2O. The Z-guggulsterone/GS (Selleck, Houston,

(12) Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelial–mesenchymal transition in a mouse model of chronic kidney diseaseGenes & DiseasesNovember 1, 2022Xin Yan, Rui Peng, Yilu Ni, Lei Chen, Qingling He, Qianyin Li, Qin Zhou(Santa Cruz, CA, USA). Rabbit anti-TTC36 was manufactured form previous work.26 Human TGF-β1 protein (10804-HNAC) was bought from SinoBiological (Beijing, China). To process Immunohistochemical (IHC) staining, SP

(13) Lymph node fibroblastic reticular cells preserve a tolerogenic niche in allograft transplantation through laminin Î±4Journal of Clinical InvestigationJuly 1, 2022Lushen Li, Marina W. Shirkey, Tianshu Zhang, Wenji Piao, Xiaofei Li, Jing Zhao, Zhongcheng Mei, Yizhan Guo, Vikas Saxena, Allison Kensiski, et al.and BSA (product number A8531) were from Sigma-Aldrich. IL-2 (catalog 51061-MNAE) and TGF-β (catalog 10804-HNAC) were from Sino Biological US. Mouse CCL21 (catalog RND-AF457) was from R&D Systems. DMEM (catalog 10-013-CV)

(14) Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosisActa pharmacologica SinicaJuly 1, 2022Dong Y, Tang BX, Wang Q, Zhou LW, Li C, Zhang X, Sun DD, Sun X, Zhang XM, Xiong B, et al.

(15) LC3A-mediated autophagy regulates lung cancer cell plasticityAutophagyApril 1, 2022Miao CC, Hwang W, Chu LY, Yang LH, Ha CT, Chen PY, Kuo MH, Lin SC, Yang YY, Chuang SE, et al.

(16) ZLN005 Alleviates In Vivo and In Vitro Renal Fibrosis via PGC-1α-Mediated Mitochondrial HomeostasisPharmaceuticals (Basel, Switzerland)March 31, 2022Zhu P, Ma H, Cui S, Zhou X, Xu W, Yu J, Li J.(HY-17538) and fenofibrate (HY-17356) were purchased from MedChemExpress (Shanghai, China). TGF-β1 (10804-HNAC) was purchased from Sino Biological (Beijing, China). Hoechst 33342 (C1022), JC-1 kit (C2006) and TMRE

(17) Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathwayCanadian journal of physiology and pharmacologyFebruary 1, 2022Wang H, Feng Z, Han X, Xing Y, Zhang X.

(18) Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cellsActa pharmacologica SinicaDecember 1, 2021Zhang X, Dong Y, Li WC, Tang BX, Li J, Zang Y.

(19) Knockdown of lncRNA XIST inhibited apoptosis and inflammation in renal fibrosis via microRNA-19b-mediated downregulation of SOX6Molecular immunologyNovember 1, 2021Xia WP, Chen X, Ru F, He Y, Liu PH, Gan Y, Zhang B, Li Y, Dai GY, Jiang ZX, et al.

(20) Sauchinone inhibits the proliferation, migration and invasion of breast cancer cells by suppressing Akt-CREB-MMP13 signaling pathwayBioscience reportsOctober 29, 2021Kim NH, Sung NJ, Shin S, Ryu DS, Youn HS, Park SA.human/mouse transforming growth factor-β1 (TGF-β1) were obtained from SinoBiological (Beijing, China, Cat#. 10804-HNAC/50698-M08H). Anti-phospho-STAT3 (Cat#. 9145), anti-STAT3 (Cat#. 9139), anti-phospho-CREB (Cat#. 9198),

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Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein

Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein from Sino Biological, Inc.

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